MCB 1200 is a 12 sample low cost magnetic
purification device for the extraction of nucleic acids for use in
research and molecular diagnostic applications. It provides rapid
and reproducible extraction of DNA, RNA, mRNA viruses,
proteins and microorganisms. Combining mixing and separation in a
single compact unit MCB 1200 offers breakthrough improvements in
product purity and yield. The absence of fluid shear means that
very large fragments of DNA can be obtained.
MCB 1200 is
easy to operate via a keypad touch panel, providing various modes
of mixing for the optimization of extraction protocol. The generic
extraction protocol means that device can be used with most
commercially available magnetic particle kits and allows easy
adaptation with manual protocols. Twelve sample volumes in the
range 5 – 100 µl may be used for extraction in 1.5 ml micro
centrifuge tubes.
The small
size of the device permits its use inside sterile hoods or cold
rooms. As there is no need to shake, MCB 1200 eliminates the
possible biohazard risks arising from the sample entrapment inside
the caps of micro centrifuge tubes.
Under
the OEM label miniMag, MCB 1200 has been successfully used in
molecular diagnostics. It has been clinically validated for the
extraction HIV
RNA, HBV DNA, CMV mRNA, Mycobacterium tuberculosis, Legionella
pneumophilia RNA, Bordetella Petrusis RNA, Mycoplasma pneumoniae
RNA using whole blood, plasma, serum, CSF, Throat Swabs,
Sputum and stool. (Please refer to “List of Publications”).
